

Half of the mice in each group underwent a passive avoidance test on the 4th day, and the other underwent the test on the 18th day, which lasted for 6 days before euthanasia for analysis of brain pathology and immunohistochemistry for ChAT.

One hundred Kunming mice were randomized into control group (N = 20), sham group (N = 20) and I/R group (N = 60), which was equally divided into 3 subgroups according to the ischemia time (20, 30 and 40 min). The aim of this study was to investigate the effects of partial hepatic ischemia/reperfusion (I/R) on postoperative cognitive function in mice. This preliminary evaluation combined with a reduction in hospital cardiac arrest rates suggest that the multiprofessional RESPOND course (in conjunction with an early warning tool and response system) is successful as part of a targeted strategy to promote patient safety within a children's hospital. Despite a poor response to the second survey, 18% (12 of 65) of respondents remained positive about the impact of the course. Overwhelmingly participants found the course positive, with the most frequently cited benefit being improved multidisciplinary communication. Sixty-five participants undertook the RESPOND course over four separate days.
Rsvp full meaning free#
Data were analysed descriptively and by simple thematic analysis of free text responses. To describe the development of the RESPOND course and present a preliminary evaluation of the first four courses.Ī written postcourse survey was completed by participants (junior doctors, medical students, nurses and health care assistants) immediately after the course and an electronic survey completed three months later in a large children's hospital in the North West of England. In response to this, a new 1-day course called RESPOND (Recognising Signs of Paediatric hOspital iNpatients Deterioration) was developed. Issues around the deterioration of hospitalised children are known: the failure to observe and monitor patients adequately, a failure to recognise the deteriorating patient, a failure to communicative effectively within the healthcare team and a failure to respond appropriately or in a timely manner (Pearson, 2008 NPSA, 2009). Contextual factors impacting care for the deteriorating patient could be addressed in further attempts to deal with this issue. This work can be considered as a first effort in modelling the concept of patient deterioration, which could be specific to ACU.Relevance to clinical practiceThe findings suggest that it might be relevant to include subjective indicators of patient deterioration in track and trigger systems and educational efforts. Contextual factors relating to acute care units (ACU) appear as barriers to optimal care of the deteriorating patient. Contextual factors, processes and consequences are also explored.Conclusionsįrom the perspectives of acute care and intensive care nurses, patient deterioration can be defined as an evolving, predictable and symptomatic process of worsening physiology towards critical illness. There are variations between acute care and intensive care unit nurses' accounts of this concept, particularly regarding the validity of patient deterioration indicators. Even if resources exist to call for intensive care nurses' help, acute care nurses use them infrequently and the problem of unattended patient deterioration remains.DesignDimensional analysis was used as a framework to analyze papers retrieved in a nursing-focused database.MethodA thematic analysis of 34 papers (2002–2012) depicting acute care and intensive care unit nurses' perspectives on patient deterioration was conducted.FindingsNo explicit definition of patient deterioration was retrieved in the papers.

AimTo explore the variations between acute care and intensive care nurses' understanding of patient deterioration according to their use of this term in published literature.BackgroundĮvidence suggests that nurses on wards do not always recognize and act upon patient deterioration appropriately.
